Parkinson's

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Parkinson’s disease affects much more than how a person moves. Very often Parkinson’s disease affects how someone thinks and learns. The Herman-Darrow Lab is committed to understanding and improving cognitive function affected by Parkinson’s disease by isolating brain circuits relevant to cognition and optimizing deep brain stimulation to address cognition.

UDALL - STUDY AND IMPROVE DBS FOR PARKINSON’S DISEASE

The University of Minnesota (UMN) Udall Center will focus on understanding the electrophysiological features that underlie the motor signs of Parkinson’s disease (PD) and developing new deep brain stimulation (DBS) strategies to treat them by doing cognitive tasks intra-operatively. Our goals are to characterize the role of cognitive hyperdirect pathway (DLPFC- STN) during a behavioral task of variable cognitive effort and compare the independent and synchronized oscillatory lfp activity between STN/GPi and DLPFC during a task of variable cognitive effort with and without DBS stimulation.

COLLABORATORS